New insights to the mechanisms driving cholangiocarcinoma

An enormous unmet clinical need exists for novel therapies in cholangiocarcinoma (cancer of the bile ducts). This disease has a poor prognosis; patients often present too late for the only curative procedure - surgical resection, and investigations to obtain tissue for diagnostic confirmation are invasive and often inconclusive. There is currently no serum biomarker of the disease, which would aid early dia...

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AMMF’s Conference 2017 – Presentations

Here we share some of the presentations from AMMF's Cholangiocarcinoma Conference, held on 11th May 2017. (Please note, we are unable to share the research presentations as much of the work we heard about is as yet unpublished and, for that reason, must remain confidential.) To download Dr Shahid Khan's presentation, “Cholangiocarcinoma - An overview”, click here       ...

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The BILCAP study results …

With the kind permission of Professor John Primrose, AMMF is now able to share the BILCAP presentation slides from the ASCO 2017 meeting. These slides show details of the BILCAP study and its outcome.  The study looked at whether or not giving cholangiocarcinoma patients Capecitabine chemotherapy following resection would be beneficial. The outcome is positive - Capecitabine will now be recommended t...

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BILCAP results show chemo improves survival

AMMF welcomes the encouraging results announced today by Cancer Research UK following the BILCAP trial into the use of the chemotherapy drug Capecitabine (Xeloda) for bile duct cancer (cholangiocarcinoma) patients following surgery. The three year survival improved by almost a quarter (23 per cent) in patients who were given Capecitabine, and the average survival was increased to 53 months from 36 months...

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AMMF’s Cholangiocarcinoma Conference 2017

AMMF will bring together scientists, researchers, medics and patients from around the world at its conference dedicated exclusively to cholangiocarcinoma, on 11 May, 2017 at the Radisson Blu Hotel, Stansted Airport, Essex. With the date just a couple of weeks away, a press release has now been distributed sharing information on what promises to be a very interesting and thought provoking day ... &...

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AMMF CEO interviewed by Pan European Networks journal …

AMMF CEO Helen Morement was recently interviewed by the Pan European Networks journal and, in a 3-page article, discusses some of the known and suspected causes of cholangiocarcinoma, why diagnosis remains so difficult, current and future treatment options, as well as the wider work of the charity throughout the UK and beyond. With the article published just ahead of the second World Cholangiocarcinoma Day...

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AMMF’s brochure – updated …

AMMF’s brochure has been updated and is now available in two versions - a printed version and a download version available from our website. Simple and straightforward, this 6-page brochure contains information on AMMF and its aims, and provides details on cholangiocarcinoma in an easy to understand way. Everyone can use the brochure to raise the awareness of cholangiocarcinoma and of AMMF - make su...

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ESMO Guidelines – SIRT an option for iCC

The new ESMO Biliary Cancer Guidelines indicate Selective Internal Radiation Therapy (SIRT) with Y-90 Microspheres as an option for post-chemotherapy treatment of intrahepatic cholangiocarcinoma (iCCA). The new ESMO1 guidelines on biliary cancers2 were published in September 2016 as a supplement to the Annals of Oncology. Their lead author, Professor Juan Valle of the Christie NHS Foundation Trust, Univers...

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PCI Biotech CCA study selected for presentation

Oslo: October 17, 2016 – PCI Biotech, the cancer focused biopharmaceutical company, announced that an abstract with results from their Phase I cholangiocarcinoma study had been selected for oral presentation as late-breaking news at this week's United European Gastroenterology (UEG) conference in Vienna, Austria. The results will be presented by Dr. Alexander Dechêne, University Hospital Essen, Germany,...

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Ambling around the world!

Thank you to everyone who took part in the first ever ‘Amble for AMMF’ on Sunday 4th September, 2016. This event caught the imagination of hundreds of people who joined in and ambled in many parts of the world - across the UK, in Ireland, the USA, France and even Eastern Siberia! Through the generosity of AMMF's Amblers, an astounding £10,000 was raised which will be an enormous help with the ch...

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