Institute of Hepatology

Research Fellow – Dr Gemma Choy

Dr Gemma Choy’s work has involved investigating whether the MAPK signalling pathway allows intrahepatic cholangiocarcinoma cell proliferation.  The project has shown results demonstrating that enhanced activation of MAPK signalling does appear important for cell proliferation, and suggests that targeting this with a chemical inhibitor may prove to be a therapeutic strategy for intrahepatic cholangiocarcinoma.

Dr Choy presented this work at the international meeting of the Digestive Disorders Federation in London in June 2015.

And her AMMF supported work was also published in the GUT Journal during 2015.  To see the abstract for the paper, “PTH-115 Inhibition of mapk signalling promotes cell cycle arrest and sensitises intrahepatic cholangiocarcinoma cells to chemotherapy” click here

Dr Choy presenting her AMMF-funded work at the DDF meeting in London, June 2015