ESMO Guidelines – SIRT an option for iCC

The new ESMO Biliary Cancer Guidelines indicate Selective Internal Radiation Therapy (SIRT) with Y-90 Microspheres as an option for post-chemotherapy treatment of intrahepatic cholangiocarcinoma (iCCA). The new ESMO1 guidelines on biliary cancers2 were published in September 2016 as a supplement to the Annals of Oncology. Their lead author, Professor Juan Valle of the Christie NHS Foundation Trust, Univers...

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PCI Biotech CCA study selected for presentation

Oslo: October 17, 2016 – PCI Biotech, the cancer focused biopharmaceutical company, announced that an abstract with results from their Phase I cholangiocarcinoma study had been selected for oral presentation as late-breaking news at this week's United European Gastroenterology (UEG) conference in Vienna, Austria. The results will be presented by Dr. Alexander Dechêne, University Hospital Essen, Germany,...

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Edinburgh study identifies CC trigger …

AMMF is delighted to see that the positive research findings of work the charity has been co-funding at the University of Edinburgh have been published in the Proceedings of the National Academy of Sciences. The Edinburgh team have identified a molecule that is a key driver in the development of bile duct cancer (cholangiocarcinoma). They have shown that this molecule - Notch 3 - triggers a pathway o...

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AMMF’s research awards – now in excess of £0.5m

Since AMMF was founded in 2002, one of the charity’s major objectives has been to support specialised research teams in their work to find the causes, methods of earlier diagnosis and effective treatments for cholangiocarcinoma (CC). Thanks to the unstinting and generous help of its fundraisers and donors, AMMF has awarded in excess of £0.5m (half a million pounds sterling) in grants to support cholangi...

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PCI Biotech trial report

A cancer focused biopharmaceutical company based in Norway, PCI Biotech, have recently reported an update on their phase I/II study in inoperable bile duct cancer patients. “The phase I part of the study has been completed with good tolerability and promising early signs of efficacy. The independent evaluation of the radiology data at six months from patients treated in cohort III and the expanded ...

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The Swedish study – thanks to the JNCI

A recently published Swedish study reported a link between sugary drinks and increased risk of biliary tract and gallbladder cancer. This was a large study of 70,832 Swedish adults (who did not have cancer or diabetes) who were questioned about diet. As the full report is a restricted access document, AMMF asked the Journal of the National Cancer Institute (JNCI) if they would be prepared to allow us to ...

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Updates on transplant, trials and more …

AMMF’s Helen Morement reports on the NCRI Hepatobiliary Clinical Trials group meeting, June 2016 In my capacity as a patient representative and advocate, I attend the regular NCRI Hepatobiliary Clinical Trials group meetings, where I get the opportunity to put forward questions and seek information on behalf of cholangiocarcinoma patients.   The members of this group are concerned wit...

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Sweet drinks and biliary tract cancer; is there a link?

An new study from Sweden has been much in the news lately, linking the consumption of sugary drinks, juices as well as sodas, to biliary tract cancer (bile duct cancer/cholangiocarcinoma) and gallbladder cancer: "People who consume at least two juice drinks a day had more than twice the risk of developing gallbladder tumours and a 79 per cent higher risk of cancer in the liver bile ducts, according to a ...

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AMMF joins European Cancer Patient Coalition

AMMF is pleased to have joined the  European Cancer Patient Coalition (ECPC) as a full member. ECPC is the largest European cancer patients' umbrella organisation, representing 370+ organisations in dozens of countries.  One of the coalition's main aims is to ensure no cancer is forgottten. Providing a unified voice for cancer patients across Europe, ECPC is working towards equality for all canc...

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AMMF’s “inspirational meeting”

AMMF's Information Day at Imperial College London, 10 May 2016 Malcolm Robinson, CC survivor and longstanding AMMF supporter, summed up the thoughts of many of those who attended AMMF's Information Day on 10 May at Imperial College London: “A wonderful opportunity to find out just how all the AMMF fundraising efforts of our supporters is invested in medical experts of the highest quality and dedicatio...

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